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Systems biology analysis of drivers underlying hallmarks of cancer cell metabolism

Malignant transformation is often accompanied by significant metabolic changes. To identify drivers underlying these changes, we calculated metabolic flux states for the NCI60 cell line collection and correlated the variance between metabolic states of these lines with their other properties. The an...

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Detalles Bibliográficos
Autores principales: Zielinski, Daniel C., Jamshidi, Neema, Corbett, Austin J., Bordbar, Aarash, Thomas, Alex, Palsson, Bernhard O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264163/
https://www.ncbi.nlm.nih.gov/pubmed/28120890
http://dx.doi.org/10.1038/srep41241