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Dissecting cell-type-specific roles of androgen receptor in prostate homeostasis and regeneration through lineage tracing

Androgen signals through androgen receptor (AR) to influence prostate development and cancer. How stromal and epithelial AR regulate prostate homeostasis remains unclear. Using genetic lineage tracing, we systematically investigated the role of cell-autonomous AR in different prostate epithelial cel...

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Detalles Bibliográficos
Autores principales: Xie, Qing, Liu, Yueli, Cai, Tao, Horton, Corrigan, Stefanson, Joshua, Wang, Zhu A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264212/
https://www.ncbi.nlm.nih.gov/pubmed/28112153
http://dx.doi.org/10.1038/ncomms14284