Histone deacetylase 3 regulates the inflammatory gene expression programme of rheumatoid arthritis fibroblast-like synoviocytes

OBJECTIVES: Non-selective histone deacetylase (HDAC) inhibitors (HDACi) have demonstrated anti-inflammatory properties in both in vitro and in vivo models of rheumatoid arthritis (RA). Here, we investigated the potential contribution of specific class I and class IIb HDACs to inflammatory gene expre...

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Detalles Bibliográficos
Autores principales: Angiolilli, Chiara, Kabala, Pawel A, Grabiec, Aleksander M, Van Baarsen, Iris M, Ferguson, Bradley S, García, Samuel, Malvar Fernandez, Beatriz, McKinsey, Timothy A, Tak, Paul P, Fossati, Gianluca, Mascagni, Paolo, Baeten, Dominique L, Reedquist, Kris A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Basic and Translational Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264225/
https://www.ncbi.nlm.nih.gov/pubmed/27457515
http://dx.doi.org/10.1136/annrheumdis-2015-209064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264225/
https://www.ncbi.nlm.nih.gov/pubmed/27457515
http://dx.doi.org/10.1136/annrheumdis-2015-209064

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