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Histone deacetylase 3 regulates the inflammatory gene expression programme of rheumatoid arthritis fibroblast-like synoviocytes
OBJECTIVES: Non-selective histone deacetylase (HDAC) inhibitors (HDACi) have demonstrated anti-inflammatory properties in both in vitro and in vivo models of rheumatoid arthritis (RA). Here, we investigated the potential contribution of specific class I and class IIb HDACs to inflammatory gene expre...
Autores principales: | Angiolilli, Chiara, Kabala, Pawel A, Grabiec, Aleksander M, Van Baarsen, Iris M, Ferguson, Bradley S, García, Samuel, Malvar Fernandez, Beatriz, McKinsey, Timothy A, Tak, Paul P, Fossati, Gianluca, Mascagni, Paolo, Baeten, Dominique L, Reedquist, Kris A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264225/ https://www.ncbi.nlm.nih.gov/pubmed/27457515 http://dx.doi.org/10.1136/annrheumdis-2015-209064 |
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