BAP1 dependent expression of long non-coding RNA NEAT-1 contributes to sensitivity to gemcitabine in cholangiocarcinoma

BACKGROUND: Genetic alterations in chromatin modulators such as BRCA-1 associated protein-1 (BAP1) are the most frequent genetic alteration in intrahepatic cholangiocarcinomas (CCA). We evaluated the contribution of BAP1 expression on tumor cell behavior and therapeutic sensitivity to identify ratio...

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Detalles Bibliográficos
Autores principales: Parasramka, Mansi, Yan, Irene K., Wang, Xue, Nguyen, Phuong, Matsuda, Akiko, Maji, Sayantan, Foye, Catherine, Asmann, Yan, Patel, Tushar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264287/
https://www.ncbi.nlm.nih.gov/pubmed/28122578
http://dx.doi.org/10.1186/s12943-017-0587-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264287/
https://www.ncbi.nlm.nih.gov/pubmed/28122578
http://dx.doi.org/10.1186/s12943-017-0587-x

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