Collagen Matrix Density Drives the Metabolic Shift in Breast Cancer Cells

Increased breast density attributed to collagen I deposition is associated with a 4–6 fold increased risk of developing breast cancer. Here, we assessed cellular metabolic reprogramming of mammary carcinoma cells in response to increased collagen matrix density using an in vitro 3D model. Our initia...

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Detalles Bibliográficos
Autores principales: Morris, Brett A., Burkel, Brian, Ponik, Suzanne M., Fan, Jing, Condeelis, John S., Aguire-Ghiso, Julio A., Castracane, James, Denu, John M., Keely, Patricia J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264313/
https://www.ncbi.nlm.nih.gov/pubmed/27743905
http://dx.doi.org/10.1016/j.ebiom.2016.10.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264313/
https://www.ncbi.nlm.nih.gov/pubmed/27743905
http://dx.doi.org/10.1016/j.ebiom.2016.10.012

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