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Collagen Matrix Density Drives the Metabolic Shift in Breast Cancer Cells
Increased breast density attributed to collagen I deposition is associated with a 4–6 fold increased risk of developing breast cancer. Here, we assessed cellular metabolic reprogramming of mammary carcinoma cells in response to increased collagen matrix density using an in vitro 3D model. Our initia...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264313/ https://www.ncbi.nlm.nih.gov/pubmed/27743905 http://dx.doi.org/10.1016/j.ebiom.2016.10.012 |