IL-1β induces apoptosis and autophagy via mitochondria pathway in human degenerative nucleus pulposus cells

IL-1β has been reported highly expressed in degenerative intervertebral disc, and our previous study indicated IL-1β facilitates apoptosis of human degenerative nucleus pulposus (NP) cell. However, the underlying molecular mechanism remains unclear. We here demonstrate that IL-1β played a significan...

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Detalles Bibliográficos
Autores principales: Shen, Jieliang, Xu, Shengxi, Zhou, Hao, Liu, Huzhe, Jiang, Wei, Hao, Jie, Hu, Zhenming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264394/
https://www.ncbi.nlm.nih.gov/pubmed/28120948
http://dx.doi.org/10.1038/srep41067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264394/
https://www.ncbi.nlm.nih.gov/pubmed/28120948
http://dx.doi.org/10.1038/srep41067

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