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IL-1β induces apoptosis and autophagy via mitochondria pathway in human degenerative nucleus pulposus cells
IL-1β has been reported highly expressed in degenerative intervertebral disc, and our previous study indicated IL-1β facilitates apoptosis of human degenerative nucleus pulposus (NP) cell. However, the underlying molecular mechanism remains unclear. We here demonstrate that IL-1β played a significan...
Autores principales: | Shen, Jieliang, Xu, Shengxi, Zhou, Hao, Liu, Huzhe, Jiang, Wei, Hao, Jie, Hu, Zhenming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264394/ https://www.ncbi.nlm.nih.gov/pubmed/28120948 http://dx.doi.org/10.1038/srep41067 |
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