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H19 Noncoding RNA, an Independent Prognostic Factor, Regulates Essential Rb-E2F and CDK8-β-Catenin Signaling in Colorectal Cancer

The clinical significance of long noncoding RNAs (lncRNAs) in colorectal cancer (CRC) remains largely unexplored. Here, we analyzed a large panel of lncRNA candidates with The Cancer Genome Atlas (TCGA) CRC dataset, and identified H19 as the most significant lncRNA associated with CRC patient surviv...

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Detalles Bibliográficos
Autores principales: Ohtsuka, Masahisa, Ling, Hui, Ivan, Cristina, Pichler, Martin, Matsushita, Daisuke, Goblirsch, Matthew, Stiegelbauer, Verena, Shigeyasu, Kunitoshi, Zhang, Xinna, Chen, Meng, Vidhu, Fnu, Bartholomeusz, Geoffrey A., Toiyama, Yuji, Kusunoki, Masato, Doki, Yuichiro, Mori, Masaki, Song, Shumei, Gunther, Jillian R., Krishnan, Sunil, Slaby, Ondrej, Goel, Ajay, Ajani, Jaffer A., Radovich, Milan, Calin, George A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264449/
https://www.ncbi.nlm.nih.gov/pubmed/27789274
http://dx.doi.org/10.1016/j.ebiom.2016.10.026