Thrombospondin-2 promotes prostate cancer bone metastasis by the up-regulation of matrix metalloproteinase-2 through down-regulating miR-376c expression

BACKGROUND: Thrombospondin-2 (TSP-2) is a secreted matricellular glycoprotein that is found to mediate cell-to-extracellular matrix attachment and participates in many physiological and pathological processes. The expression profile of TSP-2 on tumors is controversial, and it up-regulates in some ca...

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Detalles Bibliográficos
Autores principales: Chen, Po-Chun, Tang, Chih-Hsin, Lin, Liang-Wei, Tsai, Chun-Hao, Chu, Cheng-Ying, Lin, Tien-Huang, Huang, Yuan-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264454/
https://www.ncbi.nlm.nih.gov/pubmed/28122633
http://dx.doi.org/10.1186/s13045-017-0390-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264454/
https://www.ncbi.nlm.nih.gov/pubmed/28122633
http://dx.doi.org/10.1186/s13045-017-0390-6

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