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Thrombospondin-2 promotes prostate cancer bone metastasis by the up-regulation of matrix metalloproteinase-2 through down-regulating miR-376c expression

BACKGROUND: Thrombospondin-2 (TSP-2) is a secreted matricellular glycoprotein that is found to mediate cell-to-extracellular matrix attachment and participates in many physiological and pathological processes. The expression profile of TSP-2 on tumors is controversial, and it up-regulates in some ca...

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Detalles Bibliográficos
Autores principales:	Chen, Po-Chun, Tang, Chih-Hsin, Lin, Liang-Wei, Tsai, Chun-Hao, Chu, Cheng-Ying, Lin, Tien-Huang, Huang, Yuan-Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264454/ https://www.ncbi.nlm.nih.gov/pubmed/28122633 http://dx.doi.org/10.1186/s13045-017-0390-6

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