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Integrated genome-wide analysis of expression quantitative trait loci aids interpretation of genomic association studies

BACKGROUND: Identification of single nucleotide polymorphisms (SNPs) associated with gene expression levels, known as expression quantitative trait loci (eQTLs), may improve understanding of the functional role of phenotype-associated SNPs in genome-wide association studies (GWAS). The small sample...

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Detalles Bibliográficos
Autores principales: Joehanes, Roby, Zhang, Xiaoling, Huan, Tianxiao, Yao, Chen, Ying, Sai-xia, Nguyen, Quang Tri, Demirkale, Cumhur Yusuf, Feolo, Michael L., Sharopova, Nataliya R., Sturcke, Anne, Schäffer, Alejandro A., Heard-Costa, Nancy, Chen, Han, Liu, Po-ching, Wang, Richard, Woodhouse, Kimberly A., Tanriverdi, Kahraman, Freedman, Jane E., Raghavachari, Nalini, Dupuis, Josée, Johnson, Andrew D., O’Donnell, Christopher J., Levy, Daniel, Munson, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264466/
https://www.ncbi.nlm.nih.gov/pubmed/28122634
http://dx.doi.org/10.1186/s13059-016-1142-6