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TDP-43 protein variants as biomarkers in amyotrophic lateral sclerosis

BACKGROUND: TDP-43 aggregates accumulate in individuals affected by amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases, representing potential diagnostic and therapeutic targets. Using an atomic force microscopy based biopanning protocol developed in our lab, we previously isol...

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Detalles Bibliográficos
Autores principales: Williams, Stephanie M., Khan, Galam, Harris, Brent T., Ravits, John, Sierks, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264476/
https://www.ncbi.nlm.nih.gov/pubmed/28122516
http://dx.doi.org/10.1186/s12868-017-0334-7