N-(3-hydroxymethyl-β-carboline-1-yl-ethyl- 2-yl)-l-Phe: development toward a nanoscaled antitumor drug capable of treating complicated thrombosis and inflammation

It is well documented that the surfaces of cancer cells, activated platelets and inflammatory cells are rich in P-selectin. N-(3-hydroxymethyl-β-carboline-1-yl-ethyl-2-yl)-l-Phe (HMCEF) is a P-selectin inhibitor capable of simultaneously inhibiting thrombosis and inflammation. Based on the knowledge...

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Detalles Bibliográficos
Autores principales: Wu, Jianhui, Zhao, Ming, Wang, Yuji, Wang, Yaonan, Zhu, Haimei, Zhao, Shurui, Gui, Lin, Zhang, Xiaoyi, Peng, Shiqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5265142/
https://www.ncbi.nlm.nih.gov/pubmed/28176928
http://dx.doi.org/10.2147/DDDT.S123919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5265142/
https://www.ncbi.nlm.nih.gov/pubmed/28176928
http://dx.doi.org/10.2147/DDDT.S123919

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