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CD45RA Distinguishes CD4+CD25+CD127−/low TSDR Demethylated Regulatory T Cell Subpopulations With Differential Stability and Susceptibility to Tacrolimus-Mediated Inhibition of Suppression

BACKGROUND: Adoptive transfer of forkhead box protein (FOX)3(+) regulatory T (Treg) cells offers a promising strategy to reduce damage to an allograft by the recipient's immune system. Identification of cell surface markers sufficient to purify Treg cells expanded ex vivo to remove cellular con...

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Detalles Bibliográficos
Autores principales: Arroyo Hornero, Rebeca, Betts, Gareth J., Sawitzki, Birgit, Vogt, Katrin, Harden, Paul N., Wood, Kathryn J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5265687/
https://www.ncbi.nlm.nih.gov/pubmed/28118317
http://dx.doi.org/10.1097/TP.0000000000001278