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How Do Gyrating Beads Accelerate Amyloid Fibrillization?

The chemical and physical mechanisms by which gyrating beads accelerate amyloid fibrillization in microtiter plate assays are unclear. Identifying these mechanisms will help optimize high-throughput screening assays for molecules and mutations that modulate aggregation and might explain why differen...

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Detalles Bibliográficos
Autores principales: Abdolvahabi, Alireza, Shi, Yunhua, Rasouli, Sanaz, Croom, Corbin M., Chuprin, Aleksandra, Shaw, Bryan F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266089/
https://www.ncbi.nlm.nih.gov/pubmed/28122213
http://dx.doi.org/10.1016/j.bpj.2016.12.004