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Amplification of HER2 and TOP2A and deletion of TOP2A genes in a series of Taiwanese breast cancer
BACKGROUND: The prognostic relevance of topoisomerase II alpha (TOP2A) copy number change remains not well established. This study is aimed to investigate the frequency and pattern of TOP2A aberrations; to correlate TOP2A alterations with human epidermal growth factor receptor 2 (HER2) status and cl...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266154/ https://www.ncbi.nlm.nih.gov/pubmed/28079792 http://dx.doi.org/10.1097/MD.0000000000005582 |