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Amplification of HER2 and TOP2A and deletion of TOP2A genes in a series of Taiwanese breast cancer

BACKGROUND: The prognostic relevance of topoisomerase II alpha (TOP2A) copy number change remains not well established. This study is aimed to investigate the frequency and pattern of TOP2A aberrations; to correlate TOP2A alterations with human epidermal growth factor receptor 2 (HER2) status and cl...

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Detalles Bibliográficos
Autores principales: Chen, Jim-Ray, Chien, Hui-Ping, Chen, Kuo-Su, Hwang, Cheng-Cheng, Chen, Huang-Yang, Yeh, Kun-Yan, Hsieh, Tsan-Yu, Chang, Liang-Che, Hsu, Yuan-Chun, Lu, Ren-Jie, Hua, Chung-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266154/
https://www.ncbi.nlm.nih.gov/pubmed/28079792
http://dx.doi.org/10.1097/MD.0000000000005582