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Amplification of HER2 and TOP2A and deletion of TOP2A genes in a series of Taiwanese breast cancer

BACKGROUND: The prognostic relevance of topoisomerase II alpha (TOP2A) copy number change remains not well established. This study is aimed to investigate the frequency and pattern of TOP2A aberrations; to correlate TOP2A alterations with human epidermal growth factor receptor 2 (HER2) status and cl...

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Detalles Bibliográficos
Autores principales:	Chen, Jim-Ray, Chien, Hui-Ping, Chen, Kuo-Su, Hwang, Cheng-Cheng, Chen, Huang-Yang, Yeh, Kun-Yan, Hsieh, Tsan-Yu, Chang, Liang-Che, Hsu, Yuan-Chun, Lu, Ren-Jie, Hua, Chung-Ching
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer Health 2017
Materias:	5750
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266154/ https://www.ncbi.nlm.nih.gov/pubmed/28079792 http://dx.doi.org/10.1097/MD.0000000000005582

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