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Low Cytochrome Oxidase 1 Links Mitochondrial Dysfunction to Atherosclerosis in Mice and Pigs

BACKGROUND: Cytochrome oxidase IV complex regulates energy production in mitochondria. Therefore, we determined the relation of COX genes with atherosclerosis in mice and pigs. METHODS AND RESULTS: First, we compared atherosclerosis in the aortic arch of age-matched (24 weeks) C57BL/6J control (n =...

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Detalles Bibliográficos
Autores principales: Holvoet, Paul, Vanhaverbeke, Maarten, Geeraert, Benjamine, De Keyzer, Dieuwke, Hulsmans, Maarten, Janssens, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266248/
https://www.ncbi.nlm.nih.gov/pubmed/28122051
http://dx.doi.org/10.1371/journal.pone.0170307