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Low Cytochrome Oxidase 1 Links Mitochondrial Dysfunction to Atherosclerosis in Mice and Pigs
BACKGROUND: Cytochrome oxidase IV complex regulates energy production in mitochondria. Therefore, we determined the relation of COX genes with atherosclerosis in mice and pigs. METHODS AND RESULTS: First, we compared atherosclerosis in the aortic arch of age-matched (24 weeks) C57BL/6J control (n =...
Autores principales: | Holvoet, Paul, Vanhaverbeke, Maarten, Geeraert, Benjamine, De Keyzer, Dieuwke, Hulsmans, Maarten, Janssens, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266248/ https://www.ncbi.nlm.nih.gov/pubmed/28122051 http://dx.doi.org/10.1371/journal.pone.0170307 |
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