Long Non-Coding RNA HOTAIR Regulates the Proliferation, Self-Renewal Capacity, Tumor Formation and Migration of the Cancer Stem-Like Cell (CSC) Subpopulation Enriched from Breast Cancer Cells

PURPOSE: Long non-coding RNAs (lncRNAs) play important roles in the malignant behavior of cancer. HOTAIR, a well-studied lncRNA, contributes to breast cancer development, and overexpression of HOTAIR predicts a poor prognosis. However, the regulatory role of HOTAIR in the cancer stem-like cell (CSC)...

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Detalles Bibliográficos
Autores principales: Deng, Jia, Yang, Mengchang, Jiang, Rong, An, Ning, Wang, Xiaoshan, Liu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266294/
https://www.ncbi.nlm.nih.gov/pubmed/28122024
http://dx.doi.org/10.1371/journal.pone.0170860

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266294/
https://www.ncbi.nlm.nih.gov/pubmed/28122024
http://dx.doi.org/10.1371/journal.pone.0170860

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