Early Antiretroviral Therapy Is Associated with Lower HIV DNA Molecular Diversity and Lower Inflammation in Cerebrospinal Fluid but Does Not Prevent the Establishment of Compartmentalized HIV DNA Populations

Even when antiretroviral therapy (ART) is started early after infection, HIV DNA might persist in the central nervous system (CNS), possibly contributing to inflammation, brain damage and neurocognitive impairment. Paired blood and cerebrospinal fluid (CSF) were collected from 16 HIV-infected indivi...

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Detalles Bibliográficos
Autores principales: Oliveira, Michelli F., Chaillon, Antoine, Nakazawa, Masato, Vargas, Milenka, Letendre, Scott L., Strain, Matthew C., Ellis, Ronald J., Morris, Sheldon, Little, Susan J., Smith, Davey M., Gianella, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266327/
https://www.ncbi.nlm.nih.gov/pubmed/28046096
http://dx.doi.org/10.1371/journal.ppat.1006112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266327/
https://www.ncbi.nlm.nih.gov/pubmed/28046096
http://dx.doi.org/10.1371/journal.ppat.1006112

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