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Early Antiretroviral Therapy Is Associated with Lower HIV DNA Molecular Diversity and Lower Inflammation in Cerebrospinal Fluid but Does Not Prevent the Establishment of Compartmentalized HIV DNA Populations
Even when antiretroviral therapy (ART) is started early after infection, HIV DNA might persist in the central nervous system (CNS), possibly contributing to inflammation, brain damage and neurocognitive impairment. Paired blood and cerebrospinal fluid (CSF) were collected from 16 HIV-infected indivi...
Autores principales: | Oliveira, Michelli F., Chaillon, Antoine, Nakazawa, Masato, Vargas, Milenka, Letendre, Scott L., Strain, Matthew C., Ellis, Ronald J., Morris, Sheldon, Little, Susan J., Smith, Davey M., Gianella, Sara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266327/ https://www.ncbi.nlm.nih.gov/pubmed/28046096 http://dx.doi.org/10.1371/journal.ppat.1006112 |
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