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Oxidative Stress, Nrf2, and Epigenetic Modification Contribute to Anticancer Drug Resistance

Nuclear factor E2-related factor 2 (Nrf2), a transcription factor, controls the expression of genes encoding cytoprotective proteins, including antioxidant enzymes that combat oxidative and electrophilic stress to maintain redox homeostasis. However, recent studies demonstrated that, in cancer, aber...

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Detalles Bibliográficos
Autores principales: Kang, Kyoung Ah, Hyun, Jin Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Toxicology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266370/
https://www.ncbi.nlm.nih.gov/pubmed/28133507
http://dx.doi.org/10.5487/TR.2017.33.1.001