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Oxidative Stress, Nrf2, and Epigenetic Modification Contribute to Anticancer Drug Resistance
Nuclear factor E2-related factor 2 (Nrf2), a transcription factor, controls the expression of genes encoding cytoprotective proteins, including antioxidant enzymes that combat oxidative and electrophilic stress to maintain redox homeostasis. However, recent studies demonstrated that, in cancer, aber...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society of Toxicology
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266370/ https://www.ncbi.nlm.nih.gov/pubmed/28133507 http://dx.doi.org/10.5487/TR.2017.33.1.001 |