Anti-proliferative Effect of Engineered Neural Stem Cells Expressing Cytosine Deaminase and Interferon-β against Lymph Node–Derived Metastatic Colorectal Adenocarcinoma in Cellular and Xenograft Mouse Models

PURPOSE: Genetically engineered stem cells may be advantageous for gene therapy against various human cancers due to their inherent tumor-tropic properties. In this study, genetically engineered human neural stem cells (HB1.F3) expressing Escherichia coli cytosine deaminase (CD) (HB1.F3.CD) and huma...

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Detalles Bibliográficos
Autores principales: Park, Geon-Tae, Kim, Seung U., Choi, Kyung-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266401/
https://www.ncbi.nlm.nih.gov/pubmed/27188205
http://dx.doi.org/10.4143/crt.2015.503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266401/
https://www.ncbi.nlm.nih.gov/pubmed/27188205
http://dx.doi.org/10.4143/crt.2015.503

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