CBP/p300 Bromodomains Regulate Amyloid-like Protein Aggregation upon Aberrant Lysine Acetylation

Lysine acetylation is becoming increasingly recognized as a general biological principle in cellular homeostasis, and is subject to abnormal control in different human pathologies. Here, we describe a global effect on amyloid-like protein aggregation in human cells that results from aberrant lysine...

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Detalles Bibliográficos
Autores principales: Olzscha, Heidi, Fedorov, Oleg, Kessler, Benedikt M., Knapp, Stefan, La Thangue, Nicholas B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266481/
https://www.ncbi.nlm.nih.gov/pubmed/27989401
http://dx.doi.org/10.1016/j.chembiol.2016.11.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266481/
https://www.ncbi.nlm.nih.gov/pubmed/27989401
http://dx.doi.org/10.1016/j.chembiol.2016.11.009

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