De Novo Generation of a Unique Cervid Prion Strain Using Protein Misfolding Cyclic Amplification

Substantial evidence supports the hypothesis that prions are misfolded, infectious, insoluble, and protease-resistant proteins (PrP(RES)) devoid of instructional nucleic acid that cause transmissible spongiform encephalopathies (TSEs). Protein misfolding cyclic amplification (PMCA) has provided addi...

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Detalles Bibliográficos
Autores principales: Meyerett-Reid, Crystal, Wyckoff, A. Christy, Spraker, Terry, Pulford, Bruce, Bender, Heather, Zabel, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266495/
https://www.ncbi.nlm.nih.gov/pubmed/28144628
http://dx.doi.org/10.1128/mSphere.00372-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266495/
https://www.ncbi.nlm.nih.gov/pubmed/28144628
http://dx.doi.org/10.1128/mSphere.00372-16

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