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De Novo Generation of a Unique Cervid Prion Strain Using Protein Misfolding Cyclic Amplification
Substantial evidence supports the hypothesis that prions are misfolded, infectious, insoluble, and protease-resistant proteins (PrP(RES)) devoid of instructional nucleic acid that cause transmissible spongiform encephalopathies (TSEs). Protein misfolding cyclic amplification (PMCA) has provided addi...
Autores principales: | Meyerett-Reid, Crystal, Wyckoff, A. Christy, Spraker, Terry, Pulford, Bruce, Bender, Heather, Zabel, Mark D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266495/ https://www.ncbi.nlm.nih.gov/pubmed/28144628 http://dx.doi.org/10.1128/mSphere.00372-16 |
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