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A critical role for IRF5 in regulating allergic airway inflammation

Interferon regulatory factor 5 (IRF5) is a key transcription factor involved in the control of the expression of pro-inflammatory cytokine and responses to infection, however its role in regulating pulmonary immune responses to allergen is unknown. We used genetic ablation, adenoviral vector-driven...

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Detalles Bibliográficos
Autores principales: Byrne, Adam J., Weiss, Miriam, Mathie, Sara A., Walker, Simone A., Eames, Hayley L., Saliba, David, Lloyd, Clare M., Udalova, Irina A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266556/
https://www.ncbi.nlm.nih.gov/pubmed/27759022
http://dx.doi.org/10.1038/mi.2016.92