Live, Attenuated Venezuelan Equine Encephalitis Virus Vaccine (TC83) Causes Persistent Brain Infection in Mice with Non-functional αβ T-Cells

Intranasal infection with vaccine strain of Venezuelan equine encephalitis virus (TC83) caused persistent viral infection in the brains of mice without functional αβ T-cells (αβ-TCR -/-). Remarkably, viral kinetics, host response gene transcripts and symptomatic disease are similar between αβ-TCR -/...

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Detalles Bibliográficos
Autores principales: Taylor, Katherine, Kolokoltsova, Olga, Ronca, Shannon E., Estes, Mark, Paessler, Slobodan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266681/
https://www.ncbi.nlm.nih.gov/pubmed/28184218
http://dx.doi.org/10.3389/fmicb.2017.00081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266681/
https://www.ncbi.nlm.nih.gov/pubmed/28184218
http://dx.doi.org/10.3389/fmicb.2017.00081

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