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Transcriptional Regulation of Telomerase Reverse Transcriptase (TERT) by MYC
Telomerase elongates telomeres and is crucial for maintaining genomic stability. While stem cells and cancer cells display high telomerase activity, normal somatic cells lack telomerase activity primarily due to transcriptional repression of telomerase reverse transcriptase (TERT), the catalytic com...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266692/ https://www.ncbi.nlm.nih.gov/pubmed/28184371 http://dx.doi.org/10.3389/fcell.2017.00001 |