PARP Inhibitors in Reproductive System Cancers: Current Use and Developments

The repair of DNA damage is a critical cellular process governed by multiple biochemical pathways that are often found to be defective in cancer cells. The poly(ADP-ribose) polymerase (PARP) family of proteins controls response to single-strand DNA breaks by detecting these damaged sites and recruit...

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Detalles Bibliográficos
Autores principales: O’Sullivan Coyne, Geraldine, Chen, Alice P., Meehan, Robert, Doroshow, James H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Leading Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266774/
https://www.ncbi.nlm.nih.gov/pubmed/28078645
http://dx.doi.org/10.1007/s40265-016-0688-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266774/
https://www.ncbi.nlm.nih.gov/pubmed/28078645
http://dx.doi.org/10.1007/s40265-016-0688-7

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