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Interorgan Crosstalk Contributing to β-Cell Dysfunction

Type 2 diabetes mellitus (T2DM) results from pancreatic β-cell failure in the setting of insulin resistance. In the early stages of this disease, pancreatic β-cells meet increased insulin demand by both enhancing insulin-secretory capacity and increasing β-cell mass. As the disease progresses, β-cel...

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Detalles Bibliográficos
Autores principales: Tanabe, Katsuya, Amo-Shiinoki, Kikuko, Hatanaka, Masayuki, Tanizawa, Yukio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266810/
https://www.ncbi.nlm.nih.gov/pubmed/28168202
http://dx.doi.org/10.1155/2017/3605178