Cryptotanshinone Regulates Androgen Synthesis through the ERK/c-Fos/CYP17 Pathway in Porcine Granulosa Cells

The aim of the study is to investigate the molecular mechanism behind androgen reduction in porcine granulosa cells (pGCs) with Salvia miltiorrhiza Bunge extract cryptotanshinone. PGCs were isolated from porcine ovaries and identified. Androgen excess model of the pGCs was induced with the MAPK inhi...

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Detalles Bibliográficos
Autores principales: Ye, Danfeng, Li, Meifang, Zhang, Yuehui, Wang, Xinhua, Liu, Hua, Wu, Wanting, Ma, Wanying, Quan, Kewei, Ng, Ernest H. Y., Wu, Xiaoke, Lai, Maohua, Ma, Hongxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266823/
https://www.ncbi.nlm.nih.gov/pubmed/28167972
http://dx.doi.org/10.1155/2017/5985703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266823/
https://www.ncbi.nlm.nih.gov/pubmed/28167972
http://dx.doi.org/10.1155/2017/5985703

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