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Accessing gap-junction channel structure-function relationships through molecular modeling and simulations

BACKGROUND: Gap junction channels (GJCs) are massive protein channels connecting the cytoplasm of adjacent cells. These channels allow intercellular transfer of molecules up to ~1 kDa, including water, ions and other metabolites. Unveiling structure-function relationships coded into the molecular ar...

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Detalles Bibliográficos
Autores principales: Villanelo, F., Escalona, Y., Pareja-Barrueto, C., Garate, J. A., Skerrett, I. M., Perez-Acle, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267332/
https://www.ncbi.nlm.nih.gov/pubmed/28124624
http://dx.doi.org/10.1186/s12860-016-0121-9