In vitro activity of anti-malarial ozonides against an artemisinin-resistant isolate

BACKGROUND: Recently published data suggest that artemisinin derivatives and synthetic peroxides, such as the ozonides OZ277 and OZ439, have a similar mode of action. Here the cross-resistance of OZ277 and OZ439 and four additional next-generation ozonides was probed against the artemisinin-resistan...

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Detalles Bibliográficos
Autores principales: Baumgärtner, Fabian, Jourdan, Joëlle, Scheurer, Christian, Blasco, Benjamin, Campo, Brice, Mäser, Pascal, Wittlin, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267415/
https://www.ncbi.nlm.nih.gov/pubmed/28122617
http://dx.doi.org/10.1186/s12936-017-1696-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267415/
https://www.ncbi.nlm.nih.gov/pubmed/28122617
http://dx.doi.org/10.1186/s12936-017-1696-0

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