Identification of small molecule modulators of HIV-1 Tat and Rev protein accumulation

BACKGROUND: HIV-1 replication is critically dependent upon controlled processing of its RNA and the activities provided by its encoded regulatory factors Tat and Rev. A screen of small molecule modulators of RNA processing identified several which inhibited virus gene expression, affecting both rela...

Descripción completa

Detalles Bibliográficos
Autores principales: Balachandran, Ahalya, Wong, Raymond, Stoilov, Peter, Pan, Sandy, Blencowe, Benjamin, Cheung, Peter, Harrigan, P. Richard, Cochrane, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267425/
https://www.ncbi.nlm.nih.gov/pubmed/28122580
http://dx.doi.org/10.1186/s12977-017-0330-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267425/
https://www.ncbi.nlm.nih.gov/pubmed/28122580
http://dx.doi.org/10.1186/s12977-017-0330-0

Ejemplares similares