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Amyloid-like aggregation of provasopressin in diabetes insipidus and secretory granule sorting

BACKGROUND: Aggregation of peptide hormone precursors in the trans-Golgi network is an essential process in the biogenesis of secretory granules in endocrine cells. It has recently been proposed that this aggregation corresponds to the formation of functional amyloids. Our previous finding that domi...

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Detalles Bibliográficos
Autores principales: Beuret, Nicole, Hasler, Franziska, Prescianotto-Baschong, Cristina, Birk, Julia, Rutishauser, Jonas, Spiess, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267430/
https://www.ncbi.nlm.nih.gov/pubmed/28122547
http://dx.doi.org/10.1186/s12915-017-0347-9