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Amyloid-like aggregation of provasopressin in diabetes insipidus and secretory granule sorting
BACKGROUND: Aggregation of peptide hormone precursors in the trans-Golgi network is an essential process in the biogenesis of secretory granules in endocrine cells. It has recently been proposed that this aggregation corresponds to the formation of functional amyloids. Our previous finding that domi...
Autores principales: | Beuret, Nicole, Hasler, Franziska, Prescianotto-Baschong, Cristina, Birk, Julia, Rutishauser, Jonas, Spiess, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267430/ https://www.ncbi.nlm.nih.gov/pubmed/28122547 http://dx.doi.org/10.1186/s12915-017-0347-9 |
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