Acute myeloid leukemia – strategies and challenges for targeting oncogenic Hedgehog/GLI signaling

Treatment of acute myeloid leukemia (AML), an aggressive and heterogeneous hematological malignancy, remains a challenge. Despite advances in our understanding of the complex genetics and biology of AML pathophysiology, these findings have been translated to the clinic with only limited success, and...

Descripción completa

Detalles Bibliográficos
Autores principales: Aberger, Fritz, Hutterer, Evelyn, Sternberg, Christina, del Burgo, Pedro J., Hartmann, Tanja N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267446/
https://www.ncbi.nlm.nih.gov/pubmed/28122581
http://dx.doi.org/10.1186/s12964-017-0163-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267446/
https://www.ncbi.nlm.nih.gov/pubmed/28122581
http://dx.doi.org/10.1186/s12964-017-0163-4

Ejemplares similares