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Appearance of renal hemorrhage in adult mice after inoculation of patient-derived hantavirus

BACKGROUND: Hemorrhagic fever with renal syndrome (HFRS) caused by hantavirus infection is characterized by fever, renal dysfunction and hemorrhage. An animal model mimicking symptoms of HFRS remains to be established. In this study, we evaluated the pathogenicity of an HFRS patient-derived Hantaan...

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Detalles Bibliográficos
Autores principales: Shimizu, Kenta, Koma, Takaaki, Yoshimatsu, Kumiko, Tsuda, Yoshimi, Isegawa, Yuji, Arikawa, Jiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267462/
https://www.ncbi.nlm.nih.gov/pubmed/28122569
http://dx.doi.org/10.1186/s12985-017-0686-8