KRAS Mutation Test in Korean Patients with Colorectal Carcinomas: A Methodological Comparison between Sanger Sequencing and a Real-Time PCR-Based Assay

BACKGROUND: Mutations in the KRAS gene have been identified in approximately 50% of colorectal cancers (CRCs). KRAS mutations are well established biomarkers in anti–epidermal growth factor receptor therapy. Therefore, assessment of KRAS mutations is needed in CRC patients to ensure appropriate trea...

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Detalles Bibliográficos
Autores principales: Lee, Sung Hak, Chung, Arthur Minwoo, Lee, Ahwon, Oh, Woo Jin, Choi, Yeong Jin, Lee, Youn-Soo, Jung, Eun Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Pathologists and the Korean Society for Cytopathology 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267542/
https://www.ncbi.nlm.nih.gov/pubmed/28013534
http://dx.doi.org/10.4132/jptm.2016.10.03

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267542/
https://www.ncbi.nlm.nih.gov/pubmed/28013534
http://dx.doi.org/10.4132/jptm.2016.10.03

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