PACAP Protects Adult Neural Stem Cells from the Neurotoxic Effect of Ketamine Associated with Decreased Apoptosis, ER Stress and mTOR Pathway Activation

Ketamine administration is a well-established approach to mimic experimentally some aspects of schizophrenia. Adult neurogenesis dysregulation is associated with psychiatric disorders, including schizophrenia. The potential role of neurogenesis in the ketamine-induced phenotype is largely unknown. R...

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Detalles Bibliográficos
Autores principales: Mansouri, Shiva, Agartz, Ingrid, Ögren, Sven-Ove, Patrone, Cesare, Lundberg, Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5268395/
https://www.ncbi.nlm.nih.gov/pubmed/28125634
http://dx.doi.org/10.1371/journal.pone.0170496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5268395/
https://www.ncbi.nlm.nih.gov/pubmed/28125634
http://dx.doi.org/10.1371/journal.pone.0170496

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