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PACAP Protects Adult Neural Stem Cells from the Neurotoxic Effect of Ketamine Associated with Decreased Apoptosis, ER Stress and mTOR Pathway Activation
Ketamine administration is a well-established approach to mimic experimentally some aspects of schizophrenia. Adult neurogenesis dysregulation is associated with psychiatric disorders, including schizophrenia. The potential role of neurogenesis in the ketamine-induced phenotype is largely unknown. R...
Autores principales: | Mansouri, Shiva, Agartz, Ingrid, Ögren, Sven-Ove, Patrone, Cesare, Lundberg, Mathias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5268395/ https://www.ncbi.nlm.nih.gov/pubmed/28125634 http://dx.doi.org/10.1371/journal.pone.0170496 |
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