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Numerical Simulations Reveal Randomness of Cu(II) Induced Aβ Peptide Dimerization under Conditions Present in Glutamatergic Synapses

The interactions between the Aβ(1–40) molecules species and the copper ions (Cu(II)) were intensively investigated due to their potential role in the development of the Alzheimer Disease (AD). The rate and the mechanism of the Cu(II)—Aβ complexes formation determines the aggregation pathway of the A...

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Detalles Bibliográficos
Autores principales: Goch, Wojciech, Bal, Wojciech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5268396/
https://www.ncbi.nlm.nih.gov/pubmed/28125716
http://dx.doi.org/10.1371/journal.pone.0170749