Correlated 5-Hydroxymethylcytosine (5hmC) and Gene Expression Profiles Underpin Gene and Organ-Specific Epigenetic Regulation in Adult Mouse Brain and Liver

BACKGROUND: DNA methylation is an epigenetic mechanism essential for gene regulation and vital for mammalian development. 5-hydroxymethylcytosine (5hmC) is the first oxidative product of the TET-mediated 5-methylcytosine (5mC) demethylation pathway. Aside from being a key intermediate in cytosine de...

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Detalles Bibliográficos
Autores principales: Lin, I-Hsuan, Chen, Yi-Fan, Hsu, Ming-Ta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5268415/
https://www.ncbi.nlm.nih.gov/pubmed/28125731
http://dx.doi.org/10.1371/journal.pone.0170779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5268415/
https://www.ncbi.nlm.nih.gov/pubmed/28125731
http://dx.doi.org/10.1371/journal.pone.0170779

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