Selective Inhibition of Prostasin in Human Enterocytes by the Integral Membrane Kunitz-Type Serine Protease Inhibitor HAI-2

Mutations of hepatocyte growth factor activator inhibitor (HAI)-2 in humans cause sodium loss in the gastrointestinal (GI) tract in patients with syndromic congenital sodium diarrhea (SCSD). Aberrant regulation of HAI-2 target protease(s) was proposed as the cause of the disease. Here functional lin...

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Detalles Bibliográficos
Autores principales: Shiao, Frank, Liu, Li-Ching O., Huang, Nanxi, Lai, Ying-Jung J., Barndt, Robert J., Tseng, Chun-Che, Wang, Jehng-Kang, Jia, Bailing, Johnson, Michael D., Lin, Chen-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5268426/
https://www.ncbi.nlm.nih.gov/pubmed/28125689
http://dx.doi.org/10.1371/journal.pone.0170944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5268426/
https://www.ncbi.nlm.nih.gov/pubmed/28125689
http://dx.doi.org/10.1371/journal.pone.0170944

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