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Novel Mutant AAV2 Rep Proteins Support AAV2 Replication without Blocking HSV-1 Helpervirus Replication

As their names imply, parvoviruses of the genus Dependovirus rely for their efficient replication on the concurrent presence of a helpervirus, such as herpesvirus, adenovirus, or papilloma virus. Adeno-associated virus 2 (AAV2) is such an example, which in turn can efficiently inhibit the replicatio...

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Detalles Bibliográficos
Autores principales: Seyffert, Michael, Glauser, Daniel L., Schraner, Elisabeth M., de Oliveira, Anna-Paula, Mansilla-Soto, Jorge, Vogt, Bernd, Büning, Hildegard, Linden, R. Michael, Ackermann, Mathias, Fraefel, Cornel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5268427/
https://www.ncbi.nlm.nih.gov/pubmed/28125695
http://dx.doi.org/10.1371/journal.pone.0170908