Lung Basal Stem Cells Rapidly Repair DNA Damage Using the Error-Prone Nonhomologous End-Joining Pathway

Lung squamous cell carcinoma (SqCC), the second most common subtype of lung cancer, is strongly associated with tobacco smoking and exhibits genomic instability. The cellular origins and molecular processes that contribute to SqCC formation are largely unexplored. Here we show that human basal stem...

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Detalles Bibliográficos
Autores principales: Weeden, Clare E., Chen, Yunshun, Ma, Stephen B., Hu, Yifang, Ramm, Georg, Sutherland, Kate D., Smyth, Gordon K., Asselin-Labat, Marie-Liesse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5268430/
https://www.ncbi.nlm.nih.gov/pubmed/28125611
http://dx.doi.org/10.1371/journal.pbio.2000731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5268430/
https://www.ncbi.nlm.nih.gov/pubmed/28125611
http://dx.doi.org/10.1371/journal.pbio.2000731

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